Sunday, March 22, 2015

Particle Size in Relation to Disease



Pneumoconiosis is the disease associated with inhaling dust particles, and is defined as the reaction of the lung tissue to the presence of dust. When inhaling dust particles or any other type of particle into your lungs, it may cause some kind of effect on the body, or may show no signs at all. Inhaling dust particles can stimulate different reactions and cause an increase in the production or secretion of mucus, when breathing in these particles they can also cause an inflammation of tissues. “Many dusts, when inhaled, can cause changes in lung tissue that affect the lungs breathing or gas exchange functions. The most sever response would be changes in the tissues that lead to sever lung damage or to the development of cancer.”

According to the Canadian Centre for Occupational Health and Safety, “inhalation is the most important route of exposure in the workplace.” Particulates deposited in the lungs can happen through interception, impaction, sedimentation and diffusion. Interception is when a particle is stopped when reaching the surface of the airway passage. Impaction is when the particles are dispersed into the air and travel on the original path. Sedimentation is the gravitational forces and resistance of the particle staying up and diffusion is the motion of particles, this form deposits the particles on the lung walls. 

The National Institute for Occupational Safety and Health stated, “Studies have indicated that low solubility nanoparticles are more toxic than larger particles on a mass for mass basis.” When breathing in different types of particles our bodies are exposed to a large number of diseases. Many are not detected immediately; they can develop or worsen over time. The Environmental Protection Agency states that “the size of particles is directly linked to their potential for causing health problems. Small particles less than 10 micrometers in diameter pose the greatest problems because they get deep into your lungs and some may even get into your bloodstream.”



Basics of Industrial Hygiene by Debra Nims

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